Welcome to DOLPHIN’s documentation!
DOLPHIN is a Python package for analysis single-cell RNA-seq at exon level including cell clusters, differential gene analysis at exon level, alternative splicing.
Getting started with DOLPHIN:
- Usage
- Tutorials
- Exon GTF Generation
- Preprocessing Full-Length Single-Cell RNA-Seq for Exon and Junction Read Counts
- Preprocessing 10X Single-Cell RNA-Seq for Exon and Junction Read Counts
- Generate Feature Matrix and Adjacency Matrix
- Setup and Train the DOLPHIN Model
- Cell Aggregation
- Alternative Splicing Events Detection
- Alternative Splicing Analysis
- Exon-Level Differential Gene Analysis (EDEG)
- Step 2: Identify Gene-Level Markers Using Exon-Level Information
- Junction-Level Differential Gene Analysis (JDEG)
- Examples
- API Documentations